Quantcast Stages of Inflammation - Oral and Maxillofacial Pathology

Share on Google+Share on FacebookShare on LinkedInShare on TwitterShare on DiggShare on Stumble Upon
Custom Search
Inflammation is a body defense mechanism that occurs regardless of the source
of injury. The inflammatory response is progressive, in stages; however, it should be
realized that various stages may exist within an injured area at the same time. The
major stages in the inflammatory process are vascular change, exudation, and repair.
The initial inflammatory response is vascular tissue injury resulting in the following
sequence of events.
a. Hyperemia. The presence of an abnormally large blood supply in which the
blood vessels are dilated and the flow of blood is slower.
b. Permeability. Increased permeability in the smaller blood vessels, allowing
the body to position blood elements in the area in order to heal the injured tissue or
combat any introduced foreign agents.
c. Exudation. The movement of fluid and blood cellular elements (exudates)
into the injured tissue(s).
d. Edema. Accumulation of fluids within the tissue(s) that then slows or
stagnates blood flow. This acts to localize the inflammatory process.
The four major signs and symptoms of inflammation are swelling, pain, heat, and
redness. Sometimes a fifth sign is disturbance of function. Swelling is the visual sign of
the accumulation of inflammatory substances (exudates) in the tissues and the
increased amount of blood in the area. The pressure of the exudates (and perhaps the
action of toxins, enzymes, and acids released from injured cells or liberated by
defensive cellular elements) on the nerve endings causes pain. The redness and heat
that accompany inflammation are because of the increased amount of blood in the area.
Inflammatory involvement of the tissue may result in disturbance of function.
The beneficial effects of inflammation are essentially fourfold. First, the
increased fluid dilutes the irritants present in the area (e.g., bacteria and their poisonous
products). Second, the blood cells engulf and often digest bacteria, dead cells, or other
debris that might cause or continue the inflammation. Third, antibodies, which are also
present in the edema fluid, neutralize toxic substances. Fourth, clotting of the edema
fluid walls off the area and prevents the irritant and the inflammation or the inflammatory
process from spreading beyond the affected site.

Medical News
Ivory Coast bans skin whitening creams
Ivory Coast has banned skin whitening creams, which are widely...
Drug developer Adaptimmune skids after IPO raises $191M
Shares of cancer drug developer Adaptimmune fell Wednesday after the...
Underappreciated cause of bowel obstruction should be included in surgical assessments
Each year, more than 10 million Americans seek medical attention,...
Post MI Survival Better When Meds Are Free (CME/CE)
(MedPage Today) -- Is this a $2-billion savings opportunity?...
Study solves ovarian cell mystery, shedding new light on reproductive disorders
Scientists at the National Institutes of Health have solved a...
16.9 million Americans gained health coverage under Affordable Care Act, study finds
Insurance coverage has increased across all types of insurance since...
Comprehensive stroke centers may improve bleeding stroke survival
People with hemorrhagic strokes (brain bleeds) are more likely to...
Stanford panel: Big issues will loom when everyone has their genomic sequence on a thumb drive
When I was a biology grad student in the early...
Physicians and the Right to Die: Anesthesiology News Report
(MedPage Today) -- Marketing 101 for anesthesiologists, and saying 'no'...
Why is Europe so fat? Questions and Answers
World Health Organization research published Wednesday contends that Europe is...
Age matters in health messages
Health interventions to increase exercise in older people could be...
Child behavior is worse when dads feel unsupported
Children are more likely to display troublesome behaviour in families...
Mixed Success for California Food Policy (CME/CE)
(MedPage Today) -- Progress from a 2004 policy seen mainly...
Viewing violent news on social media can cause trauma
Viewing violent news events via social media can cause people...
Fecal microbiota transplant cures C. diff, blocks multi-drug resistant pathogens
A fecal microbiota transplant (FMT) not only cured a case...
Psychologists aim to help Dr Google
Psychologists are to improve online health information on lung cancer...
How managers and colleagues can help staff who witness workplace aggression
Just witnessing aggression or other bad behaviour at work can...
When mom gains too much weight during pregnancy, her child is more likely to be obese
A new study conducted in collaboration between The University of...
Fat Ireland forecasts no surprise to obesity experts
Ireland's growing weight problem is linked to a range of...
Molecular homing beacon redirects human antibodies to fight pathogenic bacteria
With the threat of multidrug-resistant bacterial pathogens growing, new ideas...

Privacy Statement - Copyright Information. - Contact Us

comments powered by Disqus

Integrated Publishing, Inc.
9438 US Hwy 19N #311 Port Richey, FL 34668

Phone For Parts Inquiries: (727) 755-3260
Google +