(1) Ulcers are shallow, nonindurated (soft), and painful. They are
surrounded by a reddish border. The ulcers vary in size and often grow together.
(2) Within two to three weeks in up to 50 percent of patients, the inguinal
lymphatic nodes become tender, enlarge, and matted together. These lymph nodes
form a fluctuant abscess (bubo) in the groin (the lymph nodes turn into large ulcers).
(3) The skin over the abscess is red and shiny. This skin may break down
forming a sinus (body cavity).
(4) Autoinoculation (spread of infection from one part of the body to another
part) may form from new locations.
c. Treatment. Chancroids may heal by themselves. If this does not happen,
chancroidal lesions usually respond to treatment very well. Treat as follows:
(1) Give sulfisoxazole (Gantrisin)) in the dosage of 1 gm, 4 times a day for
10 to 14 days.
OR TCN Tetracycline, (Tetracyn)) 500 mg, four times a day for 10 to 14
Serologic tests for syphilis (STS) monthly for three months.
(4) Aspirate buboes (enlarged or inflamed lymph nodes) that are filled with
fluid to prevent the spread of infection.
d. Additional Considerations.
(1) The patient should not apply creams, lotions, or oils on or near the
genitalia or on other lesion sites. These could spread the infection.
To help prevent a recurrence of chancroid infection, tell patients to:
(a) Avoid sexual contact with persons who have chancroid infections.
Be sure condoms are used during sexual activity.
Wash the genitalia with soap and water after sexual activity.
2-11. GRANULOMA INGUINALE (DONOVANOSIS)
This is a chronic disease marked by granulomatous ulcerations in the inguinal
region and the genitalia. This infection is mildly contagious and chronic. It is most
prevalent in tropical and subtropical areas.