a. Packaging. Glycerin and glycerinated gelatin based suppositories are best
dispensed in tightly closed, glass bottles with wide mouths. They are hygroscopic
(readily absorb and retain moisture) and unless protected from the atmosphere will
absorb water. Cocoa butter and Carbowax based suppositories may be dispensed in
cardboard boxes containing partitions so that each suppository has its own
compartment. If the suppository is wrapped individually in foil, the need for
compartments is removed and such suppositories can be correctly dispensed in plain
boxes. Suppositories containing volatile ingredients such as menthol and liquefied
phenol should be dispensed in wide-mouthed, tightly closed, glass bottles.
b. Labeling. Directions on the label should specify use of the suppositories and
their site of insertion. A "Keep in Cool Place" or "Refrigerate" label should be used.
The patient should be instructed to remove the foil wrapping before insertion of the