Quantcast Classification of Ointment Bases - Compounding and Manufacturing

Share on Google+Share on FacebookShare on LinkedInShare on TwitterShare on DiggShare on Stumble Upon
Custom Search
 
  
 
(8)  It has permanency, good keeping qualities, and neither becoming rancid
nor supporting microbial growth.
(9)  It is compatible with a wide range of medicinal substances and with
other bases with which it is likely to be mixed.
(10) It releases the incorporated medication effectively to the site of
application, and if so intended, passes into or through the skin.
(11) It is washable. Unfortunately, not all ointments, creams, and pastes
meet this requirement.
5-2.
CLASSIFICATION OF OINTMENT BASES
Ointment bases can be classified according to composition and general
characteristics. The ointment base or vehicle may or may not be therapeutically active.
It may be used without active ingredients if only protection or emollient properties are
desired. Ointment bases fall into one of these classes: oleaginous, absorption,
emulsion, or water-soluble.
a. Oleaginous Ointment Bases. Oleaginous ointment bases include not only
vegetable oils and animal fats, but also hydrocarbons derived from petroleum. Because
of their nature, oils and fats become rancid and foul smelling on exposure to the
atmosphere and to light. Preservatives and antioxidants are necessary ingredients in
these bases. The hydrocarbon bases may include liquid petrolatum to lower viscosity or
white wax to raise it. White Ointment, USP is a typical combination of hydrocarbons.
(1)  Petrolatum (Vaseline). Petrolatum is a tasteless, odorless,
yellowish, greasy solid with a melting point between 38 Celsius (C) and 60C. White
petrolatum is decolorized petrolatum. It is used more frequently than yellow petrolatum.
Petrolatum is very stable, very compatible with most substances, and emollient to the
skin. The consistency can easily be varied by the incorporation of mineral oil (liquid
petrolatum) or white wax. Petrolatum-type ointment bases are more stable than
vegetable- or animal-type bases. However, all of these bases are greasy. The degree
to which they release the incorporated medication is questionable. They are able to
absorb only very small amounts of water, unless treated with cholesterol.
(2)  (Jelene (Plastibase). Jelene, a mixture of hydrocarbons in the liquid and
wax ranges, has a jelly-like consistency. It is better than petrolatum in many respects.
It maintains its consistency over a wide range of temperature without additives. It
releases medication more reliably and provides a better appearing ointment.
(3)  Silicones. Silicones, polymers of silicon and oxygen, make good
ointments for protecting the skin from moisture.
MD0809
5-3



Medical News
Immune system of newborn babies is stronger than previously thought
Contrary to what was previously thought, newborn immune T cells...
medicalxpress.com
Cancer cells adapt energy needs to spread illness to other organs
Want to understand why cancer cells metastasize? Think of Sparta....
medicalxpress.com
Sierra Leone reaches final day of Ebola lockdown
Frustrated residents complained of food shortages in some neighborhoods of...
medicalxpress.com
How Much Does That X-Ray Cost? You Can Find Out in N.H.
(MedPage Today) -- New Hampshire is among 14 states that...
medpagetoday.com
Protocol Rapidly Transforms Stem Cells
(MedPage Today) -- A seven-stage protocol building on previous work...
medpagetoday.com
Guest Article: Endpoints for Studies of Ovarian Cancer (CME/CE)
(MedPage Today) -- Two gynecologic oncologists discuss the challenges involved...
medpagetoday.com
PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include Ebola face-to-face, the...
medpagetoday.com
Ig Nobel Winners, Bad News Sandwich: That's Improbable!
(MedPage Today) -- A weekly report from our friends at...
medpagetoday.com
Grand Roundup: Top posts for the week of Sept. 14
The five most-read stories this week on Scope were: So...
scopeblog.stanford.edu
Grand Roundup: Top posts for the week of Sept. 14
The five most-read stories this week on Scope were: So...
scopeblog.stanford.edu
For Autistic Adults, Coverage Options Are Scarce
(MedPage Today) -- Once someone with autism turns 21, "they...
medpagetoday.com
Scientists discover an on/off switch for aging cells
(Medical Xpress)—Scientists at the Salk Institute have discovered an on-and-off...
medicalxpress.com
Ultrasound enhancement provides clarity to damaged tendons, ligaments
The potential was hidden in plain sight, pretty much since...
medicalxpress.com
Sierra Leone faces criticism over Ebola shutdown
Sierra Leone began the second day of a 72-hour nationwide...
medicalxpress.com
New cancer drug target involving lipid chemical messengers
More than half of human cancers have abnormally upregulated chemical...
medicalxpress.com
New Regimens Boost Optimism for Pancreatic Ca (CME/CE)
SAN FRANCISCO (MedPage Today) -- Stereotactic ablative radiation allowed 40%...
medpagetoday.com
This Week: Ebola, Interns, and Low-T Tx
(MedPage Today) -- An exclusive piece on the rising costs...
medpagetoday.com
Twenty-four percent of middle-aged and older Americans meet muscle-strengthening guidelines
Past research has shown that strength training can benefit older...
scopeblog.stanford.edu
Twenty-four percent of middle-aged and older Americans meet muscle-strengthening guidelines
Past research has shown that strength training can benefit older...
scopeblog.stanford.edu
Vitamin K antagonist plus clopidogrel feasible for PCI
(HealthDay)—Vitamin K antagonists (VKA) combined with clopidogrel may be a...
medicalxpress.com
 


Privacy Statement - Copyright Information. - Contact Us

comments powered by Disqus

Integrated Publishing, Inc.
9438 US Hwy 19N #311 Port Richey, FL 34668

Phone For Parts Inquiries: (727) 755-3260
Google +