Quantcast Classification of Ointment Bases - Compounding and Manufacturing

Share on Google+Share on FacebookShare on LinkedInShare on TwitterShare on DiggShare on Stumble Upon
Custom Search
 
  
 
(8)  It has permanency, good keeping qualities, and neither becoming rancid
nor supporting microbial growth.
(9)  It is compatible with a wide range of medicinal substances and with
other bases with which it is likely to be mixed.
(10) It releases the incorporated medication effectively to the site of
application, and if so intended, passes into or through the skin.
(11) It is washable. Unfortunately, not all ointments, creams, and pastes
meet this requirement.
5-2.
CLASSIFICATION OF OINTMENT BASES
Ointment bases can be classified according to composition and general
characteristics. The ointment base or vehicle may or may not be therapeutically active.
It may be used without active ingredients if only protection or emollient properties are
desired. Ointment bases fall into one of these classes: oleaginous, absorption,
emulsion, or water-soluble.
a. Oleaginous Ointment Bases. Oleaginous ointment bases include not only
vegetable oils and animal fats, but also hydrocarbons derived from petroleum. Because
of their nature, oils and fats become rancid and foul smelling on exposure to the
atmosphere and to light. Preservatives and antioxidants are necessary ingredients in
these bases. The hydrocarbon bases may include liquid petrolatum to lower viscosity or
white wax to raise it. White Ointment, USP is a typical combination of hydrocarbons.
(1)  Petrolatum (Vaseline). Petrolatum is a tasteless, odorless,
yellowish, greasy solid with a melting point between 38 Celsius (C) and 60C. White
petrolatum is decolorized petrolatum. It is used more frequently than yellow petrolatum.
Petrolatum is very stable, very compatible with most substances, and emollient to the
skin. The consistency can easily be varied by the incorporation of mineral oil (liquid
petrolatum) or white wax. Petrolatum-type ointment bases are more stable than
vegetable- or animal-type bases. However, all of these bases are greasy. The degree
to which they release the incorporated medication is questionable. They are able to
absorb only very small amounts of water, unless treated with cholesterol.
(2)  (Jelene (Plastibase). Jelene, a mixture of hydrocarbons in the liquid and
wax ranges, has a jelly-like consistency. It is better than petrolatum in many respects.
It maintains its consistency over a wide range of temperature without additives. It
releases medication more reliably and provides a better appearing ointment.
(3)  Silicones. Silicones, polymers of silicon and oxygen, make good
ointments for protecting the skin from moisture.
MD0809
5-3



Medical News
New radiological signs of gastric lap band slippage identified
Researchers in Ohio and Rhode Island have identified two previously...
medicalxpress.com
When it hurts to think we were made for each other
Aristotle said, "Love is composed of a single soul inhabiting...
medicalxpress.com
Piggy-backing cells hold clue to skin cancer growth (w/ Video)
Skin Cancer cells work together to spread further and faster,...
medicalxpress.com
Cuyahoga County high school students smoking at the same rate as adults
Cuyahoga County high school students are smoking tobacco products at...
medicalxpress.com
Update: Progress in Lupus Tx Slow But Sure (CME/CE)
(MedPage Today) -- Progress toward improving the treatment of systemic...
medpagetoday.com
Joblessness could kill you, but recessions could be good for your health
Being unemployed increases your risk of death, but recessions decrease...
medicalxpress.com
Study explores attitudes, preferences toward post-Sandy rebuilding
A yearlong study funded by the New Jersey Recovery Fund...
medicalxpress.com
How multiple chronic conditions are affecting older Americans’ life expectancy
One in four adults in the United States has two...
scopeblog.stanford.edu
Medicare Tests Exceptions to 3-Day Rule
(MedPage Today) -- Medicare officials have begun exempting some patients...
medpagetoday.com
Mutated gene linked to both autism and intellectual disability
Autism spectrum disorder and intellectual disability often occur together and...
medicalxpress.com
Researchers uncover an unexpected role for endostatin in the nervous system
Researchers at UC San Francisco (UCSF) have discovered that endostatin,...
medicalxpress.com
Choice bias: A quirky byproduct of learning from reward
The price of learning from rewarding choices may be just...
medicalxpress.com
Mechanism found for development of protective HIV antibodies
Scientists at Duke Medicine have found an immunologic mechanism that...
medicalxpress.com
Prediction Update: Alzheimer's Disease 2
(MedPage Today) -- In January, we asked three noted neurologists,...
medpagetoday.com
Make the Diagnosis: Irritable Rash
(MedPage Today) -- A 40-year-old woman presents for a pruritic...
medpagetoday.com
Natural products from plants protect skin during cancer radiotherapy
Radiotherapy for cancer involves exposing the patient or their tumor...
medicalxpress.com
DIY Pulse Check May Spot Atrial Fibrillation (CME/CE)
(MedPage Today) -- Peripheral pulse measurement is a simple, accurate...
medpagetoday.com
Metastatic brain tumor treatment could be on the horizon with use of SapC-DOPS
Over half of patients being seen in the clinic for...
medicalxpress.com
Identified a key molecule in flies that adjusts energy use under starvation conditions
Most scientific literature devoted to the protein p53 refers to...
medicalxpress.com
Background TV can be bad for kids
Parents, turn off the television when your children are with...
medicalxpress.com
 


Privacy Statement - Copyright Information. - Contact Us

comments powered by Disqus

Integrated Publishing, Inc.
9438 US Hwy 19N #311 Port Richey, FL 34668

Phone For Parts Inquiries: (727) 755-3260
Google +