Clonal selection theory is based upon the idea that each individual has a
population of committed lymphocytes. Their surfaces contain receptors
determining which antigens they are capable of recognizing. When unstimulated
by antigen, only small amounts of surface IgM and IgD immunoglobulin are found.
When these cells come into contact with that particular antigenic determinant, the
cells multiply and differentiate into a clone of immunoglobulin-producing plasma
cells. (para 1-7a)
The basic tenet of the template theory is that antigen penetrates an antibody-
forming cell and serves as a template or pattern for antibody synthesis. The result
is that globulin is configured to be complementary to the antigen. (para 1-7b)
Nonspecific responses represent the body's initial encounter with a foreign agent.
Two nonspecific immune responses are inflammation and phagocytosis. (para 1-8)
End of Lesson 1