d. An example is given below:
(1) Dilute a vial of procaine penicillin G for aqueous injection labeled 300,000
units so that you can administer a dose of 75,000 units. How many milliliters must be
withdrawn and injected IM to give this dose?
WHAT (DOSE) = 75,000 units = 25 = 1 of vial is your dose
(2) Thus, it might be possible to dilute a vial with:
(a) Four ml and withdraw 1 ml for your dose.
(b) Eight ml and withdraw 2 ml for your dose.
(c) Two ml and withdraw 1/2 ml for your dose.
(d) One ml and withdraw 1/4 ml for your dose.
(3) All of the above are technically correct; however, you must consider the
size of the vial and how easily the antibiotic is reconstituted to a solution or suspension.
The manufacturer suggests and recommends that 1 ml be used to dilute this product
(see Table 1-13). The vial is actually too small to accept 8 ml of diluent.