SPECIAL INSTRUCTIONS FOR EXERCISES 31 THROUGH 35.
SITUATION: A 45-pound, 7-year-old girl of average height is to begin Griseofulvin
therapy. The dose of this drug is 10mg/kg/24 -4 doses, orally. The average adult dose
is 500 mg daily in divided doses.
Each numbered term in column A below indicates a method of solving the daily
child's dose. Once you have solved the child's dose according to each method, find it in
column B and enter the corresponding letter in the blank.
___ Clark's Rule.
a. 184 mg
___ Young's Rule.
b. 243 mg
___ Calculation using mg/kg dose.
c. 205 mg
___Calculation using mg/m dose.
d. 238 mg
___Calculation as fraction of adult
e. 150 mg
dose based on surface area.
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