Since the tetracyclines are essentially the same therapeutically, the choice of one
may be based on duration of action and relative cost.
a. Tetracycline Hydrochloride (Achromycin). Tetracycline hydro-chloride is
the most frequently used member of this group, the least expensive, and associated
with the lowest incidence of side effects. It is supplied as a tablet, capsule, oral syrup,
and injection. The usual dose is 250 mg, four times daily (see discussion above).
b. Chlortetracycline Hydrochloride (Aureomycin). Chlortetracycline
hydrochloride is supplied in 1% and 3% ointments. Chlortetracycline is valuable in the
treatment of trachoma and inclusion conjunctivitis. Oral sulfonamides such as
sulfisoxazole (Gantrisin) are often used concurrently.
c. Oxytetracycline (Terramycin). Oxytetracycline has the same actions,
usage, and dosage as tetracycline. It is supplied in oral and parenteral dosage forms.
It is also available in an ophthalmic ointment, which contains polymyxin B sulfate,