(4)
Individuals hypersensitive to sulfonamides.
NOTE:
When sulfonamides are used, it is necessary for the patient to maintain an
adequate fluid intake in order to avoid crystalluria (the presence of crystals in
the urine).
3-29. TRIMETHOPRIM AND COTRIMOXAZOLE SULFAMETHOXAZOLE
(BACTRIM, SEPTRA)
Either of these medications may be indicated for the treatment of chronic urinary
tract infections evidenced by persistent bacteria, frequent recurrent infections or
infections associated with urinary tract complications such as obstruction. The dosage
of trimethroprim and cotrimoxazole is 800 mg twice a day for 10 to 14 days. DO NOT
USE these medications with patients with hepatic and renal dysfunction if the patients
have adverse reactions to these medications. Contraindications are the same as for the
medication Gantrisin (paragraph 3-28a).
3-30. AMPICILLIN (PENBRITIN, POLYCILLIN, OMNIPEN)
These are clinically indicated, broad-spectrum antibiotics that are effective in
treating genitourinary infections. The dosage of an ampicillin drug is 25 to 500 mg
every six hours for 10 to 14 days. Adverse reactions to ampicillin are limited to
sensitivity phenomena. The contraindications of this drug are those known individuals
who are sensitive to penicillin.
3-31. TETRACYCLINE (CYCLOPAR)
This broad-spectrum antibiotic is effective against gram-positive and negative
bacteria, certain mycoplasma, rickettsiae, and protozoa. The dosage is 250 mg by
mouth every six hours for 10 to 14 days.
a. Adverse Reactions to Tetracycline. Adverse reactions to this drug include
the following:
(1)
Gastrointestinal disturbance.
(2)
Skin rash.
(3)
Renal toxicity.
(4)
Hypersensitivity to the drug.
b. Contraindications to Tetracycline. Contraindications are those known to
patients who have tetracycline hypersensitivity. Use of this drug should be watched
during pregnancy. The drug may cause discoloration of the teeth, enamel hypoplasia
(failure of the enamel of the teeth to develop completely), and bone growth inhibition.
MD0579
3-26