Other host-related factors are the a_____n dose and a_____n r_____e. A greater
immune response can be expected with low doses injected f_____ly over
(long) (short) periods of time.
You've already learned that antigens are defined in terms of their reactivity with
a_____s. Likewise, all antibodies are intimately associated with their a_____s.
Antibodies belong to a group of proteins called g______s. More specifically, since
they are active in immunity, these proteins are frequently called i_____s. They are
a collection of p_____n molecules capable of specifically combining with the
a_____n that caused their formation.
Each immunoglobulin is composed of at least one basic unit or m_____r
comprised of four p_____e chains. This basic four-chain subunit consists of two
identical h_____y chains (H) and two identical l______t chains (L).
Based on structural differences in the constant regions, there are five classes of
h_____y chains. The different forms of heavy chains are designated g____a,
a_____a, mu, d_____a, and e_____n. The type of heavy chain determines the
class of the immunoglobulin. There are five classes of immunoglobulins,
designated as Ig_, Ig_, Ig_, Ig_, and Ig_. Light chains can be classified as
k_____a and l_____a on the basis of multiple structural differences in the c_____t
The immunoglobulins are divided into how many classes? __. The most common
of these classes is Ig_. In normal human adults, IgG constitutes approximately
(25%) (50%) (75%) total serum immunoglobulins. The molecule is made up of
one basic structural unit known as a m_____r, consisting of (1) (2) (3) (4) heavy
chains and (1) (2) (3) (4) light chains. IgG is the only class of immunoglobulin that
can cross the p_____a, and it is responsible for the protection of the n_____n
during the first few m_____s of life.
The third most common form of immunoglobulin in serum is Ig_. It has a
(high)(low) molecular weight. The macromolecule makes up about
(10%) (20%) (30%) of the normal serum immmunoglobulins. It exists as a
p_____r consisting of (2) (4) (6) (8) (10) heavy chains and (2) (4) (6) (8) (10) light
chains joined together by a J chain.