Test cells for ability to adsorb antibody even if agglutination does
(d) Test eluate from adsorbing cells for agglutinating activity against
cells of other unusual activities.
Test saliva for presence of H and A or B.
(f) Study blood and saliva from blood relatives to determine heritability
of the abnormality.
(3) If polyagglutinability is suspected, various lectins can be used to
delineate the different types. The condition can arise from genetically determined
antigenic activity; from activation of the T receptor or the Tn receptor by bacterial
enzymes; or from bacterial action associated with the acquired B antigen.
Polyagglutinable red blood cells are:
Agglutinated by many typing serums of human and rabbit origin.
Agglutinated by serum from all adults, regardless of ABO type.
Not agglutinated by cord serum.
(d) Not usually agglutinated by the individual's own serum.
(e) Variably agglutinated by lectins, as shown in Table 2─8.
Table 2-8. Reactions of polyagglutinable cells with lectins.