CHOLINERGIC BLOCKING AGENTS (ANTICHOLINERGIC AGENTS)
In the last lesson, the topic of cholinergic agents was discussed. Now the topic
of cholinergic blocking agents (anticholinergic agents) will be discussed. Cholinergic
blocking agents block or reduce normal parasympathetic innervation at the
postganglionic synapse (see Figure 10-1). Drugs in this category are sometimes
referred to as parasympatholytics.
Figure 10-1. The postganglionic synapse--the site of action of the
cholinergic blocking agents.
10-2. PHARMACOLOGICAL EFFECTS OF THE CHOLINERGIC BLOCKERS
The cholinergic blockers produce specific effects on certain organs in the body.
These effects are:
a. Stomach/Intestines. The effect of the cholinergic blockers on the stomach
and intestines is decreased activity.
b. Salivary Glands. The cholinergic blockers produce a drying effect.
c. Eye (Pupil). The cholinergic blockers produce dilation of the pupil