Quantcast Factors Affecting Drug Action - Drug Dosage and Theraphy

Share on Google+Share on FacebookShare on LinkedInShare on TwitterShare on DiggShare on Stumble Upon
Custom Search
 
  
 
a. The average dose, also called the usual dose, is the amount of drug that
ordinarily produces the effect for which the drug is intended. In addition to the usual
dose, the usual dose range is often indicated for many drugs in standard pharmacy
references. This provides a guide to dispensing personnel in deciding whether the
prescriber should be consulted about the correctness of a prescribed dose. The usual
dose range is the range of doses that consistently produce the effect for which the drug
is intended.
b. The minimum dose is the smallest dose that produces a therapeutic effect.
c. The maximum dose is the largest dose that can be safely administered.
d. The toxic dose is the dose that produces harmful effects.
e. The lethal dose is the dose that will result in death. The minimum lethal dose
(MLD) is the smallest amount that will cause death.
f. The single dose is the amount of a drug taken at one time. The daily dose is
the total amount of a drug taken in 24 hours. A continuous dose consists of small doses
taken at short intervals. A maintenance dose is that amount of drug taken to replace
previous doses that have been inactivated, detoxified, or excreted. The purpose of a
maintenance dose is to maintain the required concentration of the drug in the body.
2-4.
FACTORS AFFECTING DRUG ACTION
In drug administration, many factors affect the action of the medication. These
factors also affect the dose to be administered. The usual adult dose of medication as
listed in standard references, is based on the assumption that the adult weighs 150
pounds, but since the following variables influence the action of the medication, they
also may alter the quantity of the drug necessary to produce the desired results.
a. Weight. Heavy, burly clients require larger doses than weak, emaciated
ones. The doses of many drugs are calculated on a weight basis; a specified number of
grams or milligrams are administered per pound or kilogram of body weight.
b. Age. As a rule, the very young and the very old require less than the normal
adult dose. As you recall from lesson 1, several formulas are available for estimating a
child's dose when the average adult dose is known.
c. Sex. Females usually require smaller doses than males. Iron preparations
and other hematinics are exceptions to this rule because of the blood lost by women
during menstruation.
d. Race. Race can be a factor affecting drug action, since enzyme systems,
body chemistry, and stature may vary.
MD0913
2-5



Medical News
Morphine following common childhood surgery may be life threatening
Treating post-operative pain with morphine can cause life-threatening respiratory problems...
medicalxpress.com
Many women with breast cancer have poor knowledge about their condition
A new analysis has found that many women with breast...
medicalxpress.com
Medical pot only OK for sick kids failed by other drugs: MDs
With virtually no hard proof that medical marijuana benefits sick...
medicalxpress.com
Flexible work schedules improve health, sleep
Giving employees more control over their work schedules may help...
medicalxpress.com
Daily drinking increases risk of alcoholic cirrhosis
Approximately 170,000 people die from alcoholic cirrhosis of the liver...
medicalxpress.com
The 'fifth taste,' umami, could be beneficial for health
The umami taste could have an important and beneficial role...
medicalxpress.com
Patients dismissing 'trivial' symptoms could delay cancer diagnosis
People who dismiss their symptoms as trivial or worry about...
medicalxpress.com
Stress during pregnancy can affect fetal development
Stress hormones in the mother can affect foetal development, according...
medicalxpress.com
Four tobacco makers accused by French anti-smoking of collusion
A French anti-smoking association said Sunday it had filed a...
medicalxpress.com
This Week in Medicine: Healthcare Hearings in Congress; Another Pot Opinion
(MedPage Today) -- New data, old arguments, and improving outcomes....
medpagetoday.com
Breath Test to Detect IBS Masqueraders
(MedPage Today) -- Sometimes a "diagnosis of exclusion" doesn't exclude...
medpagetoday.com
Ebola mistakes should serve a lesson says WHO
The World Health Organization's chief admitted on Sunday that the...
medicalxpress.com
Will Cancer Society's Redo Be Its Undoing?
(MedPage Today) -- Jury still out on the transformation plan...
medpagetoday.com
Infant Exposure to Hunger Hormone May Spell Trouble (CME/CE)
(MedPage Today) -- Ghrelin influences hypothalamic development, may increase obesity...
medpagetoday.com
Future $$, Magic Pill: HealthLeaders Media
(MedPage Today) -- Uncertainty over future revenue and patient safety...
medpagetoday.com
PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include chlorhexidine baths in...
medpagetoday.com
British Ebola nurse discharged from hospital
A British nurse who contracted Ebola while working as a...
medicalxpress.com
Brazil finds coffee protein with morphine effect
Brazilian scientists have discovered a protein in coffee that has...
medicalxpress.com
WHO mulls reforms to repair reputation after bungling Ebola
The World Health Organization is debating how to reform itself...
medicalxpress.com
Video shows blind mother seeing baby for first time
A video that went viral this week showed a legally...
medicalxpress.com
 


Privacy Statement - Copyright Information. - Contact Us

comments powered by Disqus

Integrated Publishing, Inc.
9438 US Hwy 19N #311 Port Richey, FL 34668

Phone For Parts Inquiries: (727) 755-3260
Google +