Table 1-1. Rabies post-exposure regimen.
Section V. REACTIONS AND SIDE EFFECTS TO IMMUNIZATIONS
Because of the possibility of adverse reactions, the established dose and
schedule recommended for each vaccine should not be exceeded. All medical officers
and other personnel concerned with administering immunizations should be impressed
with the seriousness of potential reactions and precautions to be taken to prevent these
1-14. ACUTE ANAPHYLACTIC REACTIONS
These reactions usually occur within 30 minutes after injection. Circulatory
collapse and respiratory difficulties take place. These difficulties may lead rapidly to
death if not treated immediately. Local or systemic subacute allergic reactions may also
occur as well as reactions such as serum sickness which includes certain
characteristics of both the acute and subacute variety.
1-15. DELAYED REACTIONS
After several hours or a few days, some vaccines may produce local reactions
(induration, erythema, and tenderness) at the site of the injection. These reactions may
be accompanied by systemic reactions consisting of fever, headache, malaise, chills,
gastrointestinal upset, and other related symptoms. Symptomatic treatment with
antipyretic and analgesic drugs and rest is usually adequate.
a. Typhoid Vaccine. Reactions to typhoid vaccine include pain, erythema,
induration, and swelling. Fever, myalgia, headache, and malaise may also be
manifested. Typhoid vaccine should not be given with other vaccines that may produce
similar reactions. This vaccine should also be avoided during febrile illness, intensive
physical activity, and during high environmental temperatures.