Why is hyaluronidase (Wydase) used in conjunction with local anesthetics?
a. Hyaluronidase concentrates the local anesthetic in a particular area in
order that its effects might be prolonged.
b. Hyaluronidase neutralizes the local anesthetic so that undesired adverse
effects are greatly reduced.
c. Hyaluronidase is an enzyme that acts to tenderize the tissue and make
the nerves more sensitive to the effects of the local anesthetic.
Hyaluronidase increases the movement of the local anesthetic through
4. Select the caution(s) and warning(s) associated with the use of local
a. When a local anesthetic is to be injected, the plunger should be
aspirated in several planes to ensure the drug is not being injected into a vein.
Discolored solutions of local anesthetic should be thrown away.
c. A previously used vial of local anesthetic solution should never be
All the above.
Select the toxicity(ies) associated with the use of local anesthetics.
a. Large amounts of systemically absorbed local anesthetics can cause
depression of the cardiovascular system.
b. Local anesthetics, even when given in small amounts, cause tremors,
shivering, and convulsions.
Local anesthetics cause respiratory depression.
Local anesthetics tend to produce hypersensitive reactions in most