(2)
Topical. Ointment or cream--applied locally 3 to 4 times daily.
(3)
Vaginally. 100,000 to 200,000-units daily for 2 weeks.
c. Cautions and Warnings.
(1) Nystatin is not absorbed from the GI tract and is not suitable for systemic
fungal infections.
(2) Drug should be discontinued if client develops local irritation following
topical administration.
d. Adverse Reactions. Adverse reactions are relatively rare, although local
irritation may occur following topical application. Diarrhea may be associated with large
oral doses.
e. Supply. Nystatin is supplied as nystatin oral suspension (100,000 units/ml),
nystatin tablets (oral 500,000-unit tablets and vaginal 100,000-unit tablets), nystatin
ointment (100,000-units/grams), nystatin topical powder (100,000-units/grams), and
nystatin cream (100,000-units/grams). It is also available in a topical combination of
nystatin and triamcinolone acetonide cream.
6-14. IODOCHLORHYDROXYQUIN AND HYDROCORTISONE
a. Indications. Iodochlorhydroxyquin and hydrocortisone (Vioform-HC) is
possibly effective in the control of acute and chronic inflammatory skin diseases,
particularly when complicated by bacterial, protozoal, and the following fungal
conditions: tinea palmaris, t. pedis, t. cruris, t. corporis, t. axillaris, and candidiasis.
b. Usual Dosage. Apply a small amount to affected areas 3 or 4 times daily.
c. Cautions and Warnings.
(1) This preparation should not be used in the eye or topically in the
presence of tuberculosis, vaccinia, varicella, or other viral skin conditions.
(2) The client should be warned that this preparation may stain the skin,
hair, and clothing yellow.
(3) Prolonged use of this combination product can lead to the toxicities
associated with hydrocortisone. Because of this fact, the client should be switched to
plain iodochlorhydroxyquin, if available, when inflammation is no longer present.
d. Adverse Reactions.
(1)
Local burning, irritation, and itching have been noted.
MD0913
6-13