If the results for the FANA are negative, the fluorescent intensity of the cells' nuclei
is about the same as that of the (negative) (positive) control, and there is no
discernible p____n in the nucleus.
If the results are positive, the fluorescent intensity of the cells' nuclei is
(less)(greater) than the negative control, and there is a clearly dis___ble pattern in
the nucleus. Report positive controls and patients by the specific fl____t pattern
For a homogeneous pattern, there is sm__h, e__n staining of the nucleus. The
antibodies indicated are anti-native-D_ and anti-D_. The condition indicated by a
(high) (low) titer is SLE. The condition indicated by a (high) (low) titer is RA.
For a peripheral pattern, there is staining of the n___r m____e only. The antibody
indicated is anti-native-D_. The condition indicated is S_.
For a speckled pattern, there is g__y staining throughout the nucleus usually not
affecting the n___i. The antibodies indicated are anti-S_ and anti-R_. Four
possible conditions indicated are (RA) (SLE) (PSS) (SS) (MCTD).
For a nucleolar pattern, there is solid staining of the n____i. The antibodies
indicated are anti____r. The condition indicated is P_.
The FANA is a laboratory diagnostic a__d and by itself is not d_____c. Positive
results require f____r testing for specific antinuclear antibody i_____cation and
Another limitation of the FANA is that SLE patients undergoing steroid therapy
may have (negative) (positive) test results. Also, many commonly prescribed
drugs may induce (negative) (positive) results.
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