a. Lymphoblast.
(1)
Size. Ten to 18 microns in diameter.
(2) Nucleus. The nucleus has an oval or round shape and stains reddish-
purple. The nuclear chromatin is fine, well distributed, and coarser than in the
myeloblast. Chromatin is condensed at the edges of the nucleus to form a definite
nuclear membrane. One or more nucleoli are present. The nucleus is prominent with a
nucleus-cytoplasm ratio of 6:1.
(3)
Cytoplasm. The cytoplasm is deep blue with a frequent perinuclear
clear zone.
Figure 4-4a. Lymphocytic series:
a. Lymphoblast.
b. Lymphocyte.
c. Smudge Cell.
b. Prolymphocyte.
(1)
Size. Ten to 18 microns in diameter.
(2) Nucleus. The nucleus is oval and slightly indented. The nuclear
chromatin is coarse, slightly clumped, am dark purple. One light blue nucleolus is
usually present. The nucleus- cytoplasm ratio is 5:1.
(3) Cytoplasm. The cytoplasm varies from light blue to dark blue and it can
show a few red-purple ( azurophilic) granules.
Figure 4-4b. Lymphocytic series: .Prolymphocyte.
MD0853
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