c. Cautions and Warnings.
(1) This product should be used very cautiously in pregnant women and
nursing mothers, because this drug passes the placenta and is excreted in the milk and
may cause kernicterus (condition of severe neural symptoms, with high blood levels of
(2) Adequate fluid intake must be maintained in order to prevent crystalluria
(crystals in the urine) and stone formation.
(3) Sulfonamides should be given cautiously in clients with impaired renal or
hepatic function and to those with severe allergy or bronchial asthma.
(4) Use this drug cautiously in clients with glucose-6-phosphate
dehydrogenase (G6PD) deficiency.
(5) Complete blood counts should be done frequently to guard against
severe blood dyscrasias.
d. Adverse Reactions.
(1) Allergic reactions including rashes, pruritis, and fever are the most
common adverse effects.
(2) Nausea, vomiting, headache, lassitude, dizziness, mental depression,
abdominal pain, arthralgia, leukopenia, and photosensitivity may occur.
(3) Less common reactions include crystalluria, hepatotoxicity, jaundice,
and serious blood dyscrasias.
Clients with G6PD deficiency may develop hemolytic anemia.
e. Supply. Sulfisoxazole tablets, 0.5 gram each, are available.
a. Indications. Sodium sulfacetamide (Sodium Sulamyd) is used topically:
(1) For the treatment of conjunctivitis, corneal ulcer, and other superficial
As adjunctive treatment in systemic therapy of trachoma.