b. Usual Dosage.
(1) Ophthalmic solution, 15 percent. For conjunctivitis or corneal ulcer,
instill one or two drops into the lower conjunctival sac every two or three hours during
the day, but use less at night. For trachoma, use four drops every two hours with
concomitant systemic therapy with sulfonamides or tetracycline.
(2) Ophthalmic ointment, 30 percent. Apply a small amount four times daily
and at bedtime. The ointment may be used adjunctively with the solution. The ointment
is not sterile.
c. Cautions and Warnings.
(1) Sulfacetamide is contraindicated in individuals who are hypersensitive to
sulfonamide preparations.
(2)
Solutions are incompatible with silver preparations.
(3)
Ophthalmic ointments may retard corneal healing.
(4) Nonsusceptible organisms, including fungi, may proliferate with use of
these preparations.
(5) Sulfonamides are inactivated by para-aminobenzoic acid present in
purulent exudates.
(6) Use with caution in clients who are deficient in glucose-6-phosphate
dehydrogenase.
(7)
Keep in a cool place.
d. Adverse Reactions. Common side effects are fever, skin rashes, urticaria,
photosensitivity, and conjunctivitis.
e. Supply. Sodium sulfacetamide is supplied as a 15 percent ophthalmic
solution and as a 10 percent ophthalmic ointment. It is also available in combinations
called sodium sulfacetamide, phenylephrine hydrochloride, and prednisolone acetate
ophthalmic suspension and sodium sulfacetamide and prednisolone acetate ophthalmic
suspension.
MD0913
6-9
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